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Pigr antibody

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Complete information for PIGR gene (protein-coding), polymeric immunoglobulin receptor, including: function, proteins, disorders, pathways, orthologs, and expression. Polymeric immunoglobulin receptor (pIgR) is one important player of mucosal defenses, but very little is known on pIgR-mediated immune excretion of the antigens that penetrate mucosal surface in fish. Previously, we cloned the pIgR of flounder (Paralichthys olivaceus) and developed anti-pIgR antibody.

Antibody information for antibodies HPA006154, HPA012012 and CAB009454 used in analysis of ENSG00000162896 / PIGR () We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. band was detected for pIgR at approximately 110­150 kDa (as indicated) using 2.5 µg/mL of Mouse Anti­Human pIgR Monoclonal Antibody (Catalog # MAB2717). This experiment was conducted under reducing conditions and using the 12­230 kDa separation system. 35(3$5$7,21$1'6725$* band was detected for pIgR at approximately 110­150 kDa (as indicated) using 2.5 µg/mL of Mouse Anti­Human pIgR Monoclonal Antibody (Catalog # MAB2717). This experiment was conducted under reducing conditions and using the 12­230 kDa separation system. 35(3$5$7,21$1'6725$* May 03, 2018 · PIgR may also aid in S. pneumoniae meningitis, as pIgR was found to colocalize with S. pneumoniae in brain samples from human patients who had succumbed to meningitis, and anti-pIgR antibodies administered intravenously prior to infection prevented pneumococcal entry into the brain and subsequent meningitis in mice .

Jul 19, 2018 · Polymeric immunoglobulin receptor (pIgR) is one important player of mucosal defenses, but very little is known on pIgR-mediated immune excretion of the antigens that penetrate mucosal surface in fish. Previously, we cloned the pIgR of flounder (Paralichthys olivaceus) and developed anti-pIgR antibody. PIGR Antibody (Cat. No. 71-171) can be used to detect Gibbon, Gorilla, Human, Monkey, Orangutan PIGR Antibody in IHC and other applications. PIGR (arrow) was detected using the purified antibody. image 2 : Formalin-fixed and paraffin-embedded human hepatocarcinoma with PIGR Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHCPlus™ PIGR Antibody LS-B11012 is a pathologist validated IHC antibody Mouse anti-Human PIGR. Validated for ELISA,IHC,WB. Tested on 20 paraffin-embedded human tissues. Polymeric immunoglobulin receptor (pIgR) is one important player of mucosal defenses, but very little is known on pIgR-mediated immune excretion of the antigens that penetrate mucosal surface in fish. Previously, we cloned the pIgR of flounder (Paralichthys olivaceus) and developed anti-pIgR antibody.

Detection of Human pIgR by Western Blot. Western blot shows lysates of human small intestine tissue. PVDF membrane was probed with 0.2 µg/mL of Goat Anti-Human pIgR Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2717) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for pIgR at approximately 85-100 kDa (as indicated).

 

 

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Notably, human pIgR transcytoses constitutively, with or without ligand, creating both bound and free, 78 kDa SC following cleavage (3). The extracellular region of pIgR is 64%, 65% and 70% aa identical to the equivalent region in rat, mouse and porcine, respectively.

Pigr antibody

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Pigr antibody

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Rabbit Polyclonal PIGR antibody for ELISA, ICC, IF, IHC (p), WB. Order anti-PIGR antibody ABIN2506621.

Pigr antibody

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May 03, 2018 · PIgR may also aid in S. pneumoniae meningitis, as pIgR was found to colocalize with S. pneumoniae in brain samples from human patients who had succumbed to meningitis, and anti-pIgR antibodies administered intravenously prior to infection prevented pneumococcal entry into the brain and subsequent meningitis in mice .

Pigr antibody

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PIGR Antibody (C-term) (Cat. #AP8555b)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PIGR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Pigr antibody

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• Hepatocellular carcinoma-associated protein TB6 Antibody • MGC125361 Antibody • MGC125362 Antibody • Phosphatidylinositol glycan, class R Antibody • PIGR_HUMAN Antibody • Poly Ig receptor Antibody • Poly-Ig receptor Antibody • Polymeric immunoglobulin receptor Antibody • Secretory component Antibody

Pigr antibody

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This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface.

Pigr antibody

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Immunohistochemical analysis of pIgR was detected in immersion fixed frozen sections of mouse liver using Goat Anti-mouse pIgR Antigen Affinity-purified Polyclonal Antibody (Product # PA5-47402) at 1 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB (brown and counterstained with hematoxylin (blue).

Pigr antibody

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Anti-PIGR polyclonal antibody was developed using: A synthetic peptide of human PIGR. This antibody is applicable for use in: Western Blot,Immunohistochemistry,Immunoflurescence,Flow cytometry JavaScript seems to be disabled in your browser.

Pigr antibody

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May 03, 2018 · PIgR may also aid in S. pneumoniae meningitis, as pIgR was found to colocalize with S. pneumoniae in brain samples from human patients who had succumbed to meningitis, and anti-pIgR antibodies administered intravenously prior to infection prevented pneumococcal entry into the brain and subsequent meningitis in mice .

Pigr antibody

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This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

Secretory immunoglobulin (Ig)A, the most abundant mucosal Ig, is transported by the polymeric immunoglobulin receptor (pIgR). IgG antibodies, which are transported by the neonatal Fc receptor (FcRn), are also abundant in mucosal tissues and secretions, particularly in the female genitourinary tract.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Recombinant fragment corresponding to a region within amino acids 180 and 459 of PIGR (Uniprot ID#P01833) Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Addition of anti-pIgR antibody reduced IgA transcytosis to <15% of non-treated samples, suggesting that a significant amount of transcytosed IgA is mediated by pIgR. 3H1 and 1.193 antibodies were ...

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pIgR in Mouse Liver. pIgR was detected in immersion fixed frozen sections of mouse liver using Goat Anti-Mouse pIgR Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2800) at 1 µg/mL overnight at 4 °C.

Complete information for PIGR gene (protein-coding), polymeric immunoglobulin receptor, including: function, proteins, disorders, pathways, orthologs, and expression.

Rabbit Polyclonal PIGR antibody for ELISA, ICC, IF, IHC (p), WB. Order anti-PIGR antibody ABIN2506621.

Detection of Human pIgR by Western Blot. Western blot shows lysates of human small intestine tissue. PVDF membrane was probed with 0.2 µg/mL of Goat Anti-Human pIgR Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2717) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for pIgR at approximately 85-100 kDa (as indicated).

PIGR Antibody (Cat. No. 71-172) can be used to detect Gorilla, Human PIGR Antibody in IHC and other applications.

Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-Y PIGR monoclonal antibody (dilution ratio 1:60) at 4℃ overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm.

Human milk (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with PIGR antibody [N2C1], Internal (GTX110197) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

PIGR (arrow) was detected using the purified antibody. image 2 : Formalin-fixed and paraffin-embedded human hepatocarcinoma with PIGR Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Detection of Human pIgR by Western Blot. Western blot shows lysates of human small intestine tissue. PVDF membrane was probed with 0.2 µg/mL of Goat Anti-Human pIgR Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2717) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for pIgR at approximately 85-100 kDa (as indicated).

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

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  • PIGR Antibody (C-term) (Cat. #AP8555b)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PIGR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • Please note: Anti-PIGR Antibody is for research use only. It is not intended for diagnostic or therapeutic use. It is not intended for diagnostic or therapeutic use. Antibodies.com | A8817
  • PIGR Antibody (Cat. No. 71-171) can be used to detect Gibbon, Gorilla, Human, Monkey, Orangutan PIGR Antibody in IHC and other applications.
  • iiia) Secretory antibody function. Secretory IgA is the principal weapon protecting us from pathogens and toxins that might otherwise penetrate mucosal surfaces. These antibodies, whose expression was discussed in Chapter 5, are key components of the mucosal mucus and other body secretions such as saliva and tears. It is important to appreciate ...
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  • Rabbit Polyclonal PIGR antibody for ELISA, ICC, IF, IHC (p), WB. Order anti-PIGR antibody ABIN2506621.
  • pIgR in Mouse Liver. pIgR was detected in immersion fixed frozen sections of mouse liver using Goat Anti-Mouse pIgR Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2800) at 1 µg/mL overnight at 4 °C.
  • Immunohistochemical analysis of pIgR was detected in immersion fixed frozen sections of mouse liver using Goat Anti-mouse pIgR Antigen Affinity-purified Polyclonal Antibody (Product # PA5-47402) at 1 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB (brown and counterstained with hematoxylin (blue).
  • Complete information for PIGR gene (protein-coding), polymeric immunoglobulin receptor, including: function, proteins, disorders, pathways, orthologs, and expression.
  • PIGR (Polymeric Immunoglobulin Receptor) is a Protein Coding gene. Diseases associated with PIGR include Periampullary Adenocarcinoma and Protein-Energy Malnutrition. Among its related pathways are IL4-mediated signaling events and Innate Immune System.
  • Human(5284) Summary: This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface.
IHC-P image of rat skin tissue using anti-PIGR (dilution of primary antibody at 1:200) IF analysis of rat skin tissue using anti-PIGR (dilution of primary antibody at 1:200) Western blot analysis of human breast cancer tissue using PIGR antibody (Dilution of 1:500)
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  • Pigr antibody

  • Pigr antibody

  • Pigr antibody

  • Pigr antibody

  • Pigr antibody

  • Pigr antibody

  • Pigr antibody

  • Pigr antibody

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